Pituitary tumor case report pdf

This case report describes a neuroendocrine tumor net arising from enterochromaffin cells that underwent neoplastic transformation. The pituitary adenoma with calcification is a rare radiological finding and it must be distinguished from other lesions of the pituitary gland as the management and prognosis differs significantly. The pituitary gland is sometimes called the master endocrine gland because it makes hormones that affect the way many parts of the body work. In spite of the hypersecretion of gh, serum igfi was. Artemisinin is a sesquiterpene lactone usually extracted from the plant artemisia annua l. The coexistence of infundibular pituicytoma and cushings. Since then, a number of surgical and autopsy series and sporadic case reports have described metastatic tumors to the pituitary. Herein, we report a case of sellar glioblastoma with suprasellar extension with no prior radiation history who mimicked clinical and radiologic findings of a pituitary macroadenoma. He had a 10year history of altered behavior, obesity, depression, sphincter incontinence, and recent visual troubles. Thyrotropinproducing pituitary tumor is relatively rare. Case history a 30yearold japanese man who presented with recurrent ketoacidosis caused by iddm was found to have increased secretion of growth hormone gh. Pituitary tumors form in the pituitary gland, a peasized organ in the center of the brain, just above the back of the nose.

We describe a case of a thyrotropinproducing pituitary adenoma concomitant with graves disease, which was successfully treated. However, some atypical pituitary adenomas present with a high rate of proliferation and extensive invasion, suggesting a tumor with a high degree of malignancy. We report a case of a 29yearold gentleman presented electively with the complaints of deterioration of vision for four months. The pituitary lesion was found during the workup for a.

Perioperative stroke after endonasal pituitary tumor resection. In this paper, we report an atypical case of pituitary adenoma presenting as a nasal mass. Case report a 25yearold young male patient presented to neurosurgery outpatient department with the complaints of chronic headache and diminution of vision of left eye. In particular, concurrent cases associated with graves disease are extremely rare and only nine cases have been reported so far. Case report initial presentation of pituitary tumor a 31yearold man presented to his optometrist in february, 2011, with fluctuating headaches and visual changes for 2 months. Large cell neuroendocrine carcinoma lcnec is similarly rare, accounting for only 3% of all lung malignancies in adults.

The aim of this case report is to present a case of igg4related hypophysitis that mimics a pituitary tumor clinically and radiologically. Hypersecretion too much of any hormone in the body is caused by a functioning pituitary tumor 2. Fatal complication after transsphenoidal surgery of. In a few cases, they may present aggressive behavior and invade the sphenoid sinus and. Hypofractionation of pituitary adenoma new york university langone medical center 71 year old male, right handed diagnosed with prolactinoma in 2009 after he obtained a brain mri for persistent headaches imaging demonstrated a large rightsided cavernous sinus tumor extending into the parasellar region and the right. We report one case of growth hormone ghproducing tumor, occurring in the clivus, with an apparently normalsized sella. Pituitary adenoma associated with intraventricular.

We report two cases of posterior pituitary astrocytomas in middleaged women presenting as focal lesions of the neurohypophysis. Iddm accompanied by a growth hormoneproducing pituitary. Nonfunctioning pituitary macroadenoma nfpa is a tumour of the endocrine system that is virtually always benign and can be difficult to detect. In this report, we describe a patient who had a pituitary ad enoma associated with obstructive hydrocephalus treated by endoscopic transnasal transsphenoidal surgery. Nonsecretory tumors occur in and around the sellae turcica and can mimic the pituitary tumors clinically. In some patients, a dumbbelllike extension of a pituitary tumor reaches through the small opening in the diaphragm traversed by the pituitary stalk. Here you can find out all about pituitary tumors, including risk factors, symptoms, how they are found, and how they are treated. Astrocytoma, or pituicytoma, of the posterior pituitary is a relatively rare entity consisting of poorly characterized glial tumor cells.

The high proportion of p53positive cells in the tumor described in this case study was not enough to diagnose it as a carcinoma, but it was enough to indicate that this tumor should have been treated differently. A 46 years old women was admitted for headaches and impaired vision, and mri and ct revealed a sellar lesion. American brain tumor association pituitary tumors introduction the pituitary gland is a beansized organ located in the midline at the base of the brain, just behind the bridge of the nose, in a bony pouch called the sella turcica. Pituitary carcinoma is very rare and hard to diagnose. Our case represents a rare combination of two morphologically different pituitary adenomas, one producing acth and the other lh and alpha subunit. Since then, only a few case reports and individual cases extracted from larger case series have been reported in the literature. The present case indicates that benign, typically slowgrowing pituitary adenomas of oncocytic gonadotrophic type may respond to temozolomide even when the tumor consists of an admixture of mgmt. The pituitary itself is known as the master gland because it helps to control the secretion of hormones.

Clivus is an unusual location for occurrence of a pituitary adenoma, and all previous reported cases of endocrinologically active adenomas involving the clivus have been prolactinomas. In a few cases, they may present aggressive behavior and invade the sphenoid sinus and nasal cavity, causing unusual symptoms. The authors report the first case of a pituitary tumor associated with a fourth ventricle meningioma. In cases where stalk injury is likely, further resection would not be performed, and the tumor would remain untreated, as radiation therapy is not effective for gcts. The patient had been operated 18 years before due to a pituitary adenoma. Pituitary tumor case study south jersey medical report. Magnetic resonance perfusion with arterial spinlabeling asl indicated that the tumor had hyperperfusion nature fig. A single case of aneurysms due perhaps to actual tumor infiltration of the arterial wall has been reported. The skull base and sellar region are extremely rare sites for net. Here, we present a case study of this type of tumor.

Download pdf chinese neurosurgical journal biomed central. Case presentation herein we report a 51yearold caucasian woman with history of multiple sclerosis who presented with clinical evidence of hypopituitarism and twoweek history of diplopia. Pituicytoma is an uncommon noninvasive tumor of the sellar and suprasellar regions. This finding was compatible with pituitary metastasis, with. The investigators noticed that cases of multiple pituitary tumors increase the risk of failure after surgery because some tumors might not be removed completely. The three firstline investigations that are required for further analysis are urine osmolality, serum osmolality, and urinary sodium levels in addition to. In of the cases, the host tumor was a nonfunctioning adenoma, whereas the remaining five cases concerned prl, acth, and ghsecreting adenomas. Case report open access a case with transient refractive.

The problems caused by pituitary tumors fall into three general categories. In this paper we report a case of choriocarcinoma metastases to the pituitary. Nonfunctioning gonadotroph pituitary adenoma presenting as. We describe a case of lcnec of lung origin that metastasized to the pituitary gland. I have attached a typed copy of the medical report with this email as the scan copy might not be clear. Pituitary gland adenoma accounts for 520% of all central nervous system tumors in the adult population. Spontaneous regression of nonfunctioning pituitary. Case report a 37yearold manpresented to us with hairless, headache and visual disturbance in both eyes for three months.

Cureus pituitary metastasis of pulmonary large cell. Regarding metastasis to a pituitary adenoma, it is noteworthy that although tumortotumor metastasis is extremely rare, 18 published cases were found in the literature 7, 8, 20, 28, 35. Pituitary macroadenoma presenting as severe hyponatremia. This case report is presented from the patients perspective to highlight experiences that led to the eventual diagnosis of this condition. Case report suprasellar granular cell tumor of the. They chose to operate through the posterior fossa tumor. Though this is a relatively rare pathology, it is important for surgeons to monitor the volume of tumors prior to surgery in order to potentially avoid an unnecessary procedure.

Although hyponatremia is not an uncommon laboratory finding, especially in the elderly, hunting for the etiology is a challenging issue for any clinician. Pituitary carcinoma is very rare, with one study report. Pituitary macroadenomas are rare intracranial tumors. Refractive change can be caused by systemic illnesses such as lupus erythematosus, thyroid.

If you have a pituitary tumor or are close to someone who does, knowing what to expect can help you cope. A 22yearold female was admitted to the second xiangya hospital of central south university changsha, china, complaining of a headache for 20 days and blurred vision for 10 days. Among all pituitary tumor resections, only approximately 1% are found to be metastatic tumors. A 40yearold japanese woman presented with mild signs of. In this case report, we have implemented a novel therapy for a pituitary tumor using artemether, an analog of the antimalarial drug artemisinin. Pituitary tumors are mostly found to be benign adenomas, however pituitary carcinoma has been reported to comprise about 0.

A new oncogene, pituitary tumor transforming gene1 that serves as marker for endocrine malignancies have been discovered. This gene is over expressed in case of pitutary tumors. Benjamin first described a case of metastasis to the pituitary mp gland in an autopsy of a patient with disseminated melanoma. Simultaneous occurrence of cerebellar medulloblastoma and. Radiation therapy has rarely been associated with aneurysmal dilatation for nonpituitary tumors and has been reported only once after treatment of a pituitary tumor. Case report open access collision tumors of the sella. Here, we report a rare case of gct of the pituitary stalk, which is difficult to diagnose without pathologic confirmation. In this paper, we report a case of gct of the pituitary stalk and discuss the features of ct and mri for making a preoperative diagnosis.

The case is the third report of a patient with multiple pituitary tumors producing acth and growth hormone, in which both hormones caused symptoms. Case report open access a case with transient refractive change after removal of pituitary tumor hiroto ishikawa1,2, junsuke akura2, kazutaka uchida3, naohiro ikeda1, tomohiro ikeda1, cesar v borlongan4 and osamu mimura1 abstract background. The pituitary gland is an uncommon site of tumor metastasis in the brain, comprising only 1% of all intracranial metastasis. In this case report, we describe a patient with spontaneous regression of nonfunctioning pituitary adenoma. Pituitary macroadenoma presenting as a nasal tumor. Pdf sunct syndrome associated with pituitary tumor. Case report a 63yearold man underwent brain ct for a medical checkup at our hospital, and a suprasellar tumor was detected. In this case report, we described a patient with cushings disease to whom mri displayed only an infundibular wellcircumscribed lesion, but not any pituitary adenoma. Hormone deficiency too little of any pituitary hormone can be caused by a large pituitary tumor, which interferes with the pituitary glands ability to produce hormones. Hyponatremia is defined as a serum sodium level of less than 5 meql in a patient. Obstructive hydrocephalus caused by pituitary adenoma. Atypical pituitary adenoma, pituitary carcinoma, pathology, invasiveness. Although silent gonadotroph macroadenomas are relatively common, functional gonadotroph adenomas are rare.

In this tumor, about 90% of the cells were immunopositive for mgmt. Khaled a1, joarder ma2, karim b3, chandy mj4, nasir ta5. We report a case of a 66yearold patient treated for chronic idiopathic polycythemia for at least 10 years, in whom a large pituitary lesion in a cerebral computed. Appropriately, they elected not to obtain a tissue sample of the skull base mass because the diagnosis was established with a prolactin level of 6800 mgml. Pdf perioperative stroke after endonasal pituitary tumor. In this context, we report the case of a 42yearold woman suffering simultaneously from a cerebellar medulloblastoma, secondary disseminated within the spinal canal, and a pituitary macroadenoma.

Spectacles failed to improve his vision, and he was referred to a neurologist who found a. Acthsecreting pituitary carcinoma metastatic to the liver in a patient with a history of atypical pituitary adenoma and cushings disease. Polycythemia is a rare and often unrecognized manifestation of a functional gonadotroph adenoma. We report a case of a 29yearold gentleman presented electively with the complaints of. Thyrotropinproducing pituitary adenoma simultaneously. A pituitary tumor is a growth of abnormal cells in the tissues of the pituitary gland. However, pituitary metastasis of choriocarcinoma is extremely rare. Pituitary gland tumours are common constituting about a quarter. These tumors can arise in almost every organ of the body although they are most commonly found in the gastrointestinal tract and respiratory system. The few reports published to date have not reported series of sufficient size to establish the characteristic clinical, pathologic, and imaging. On initial cranial magnetic resonance imaging mri, no pituitary lesion was detected.